Cancer Genomics
Genomic and transcriptomic profiling of bladder cancer and urothelial cell carcinoma — molecular drivers, therapeutic resistance and protein–protein interaction networks in oncogenic pathways.
- Hub-gene discovery from PPI networks of transcriptomic expression
- Candidate biomarkers for bladder cancer (CERS2, EN2)
- Systematic synthesis of GWAS and biomarker evidence in bladder cancer
Oncolytic Virotherapy
Mechanisms of Newcastle disease virus (NDV) persistence in cancer cells — how a persistently infecting virus rewires the host transcriptome, and what that means for the therapeutic window.
- In vitro models of NDV persistence in bladder cancer cell lines
- Functional transcriptome analysis of persistently infected cells
- Genomic alterations in persistently infecting NDV
Genomic Surveillance & Public Health
Computational pipelines for pathogen detection and population genomics, and the systems work of embedding sequencing into national public health institutes and regional hubs across West Africa.
- Support to national public health institutes and regional sequencing hubs
- Diagnostic assay performance against circulating African genotypes
- Evidence for policy on molecular diagnostics and sequencing
Training & Open Science
Building bioinformatics capacity where it is scarcest — curricula, carpentry workshops, and the community infrastructure that keeps research open, reproducible and locally owned.
- Certified Carpentries instructor; workshop design and delivery
- Undergraduate and postgraduate genomics curricula
- Founder, Open Science Community Nigeria